Info Pelatihan



03-05 Oktober 2012

17-19 Oktober 2012

07-09 November 2012

28-30 November 2012

05-07 Desember 2012

19-21 Desember 2012


Granulation and compression are two very important processes that are carried out extensively by most pharmaceutical companies. However, the theory of granulation is little understood and the selection of a particular machine and granulation method, is often done on the basis of tradition, rather than by using strict scientific or cost-benefit criteria. The basic techniques have changed dramatically in recent years and granulation for controlled release, extrusion, spheronisation, fluidization techniques, spray drying, melt extrusion, oral dispersion technology and roller compaction are new technologies that are increasingly being used in modern pharmaceutical production, which exhibit many advantages over previously available techniques. As with granulation, compression is also little understood and why some materials/formulations will compress well whilst others compact with difficulty, is slowly being elucidated. The Course will examine current granulation and compression theory and practice. Emphasis will be made as to how this theory and practice relates to current pharmaceutical development and production, with special reference to the machinery used. Scale-Up, Transfer Technology and SUPAC will also be addressed. A particular feature of the Course will be the workshop on new melt extrusion technology. (pf)


The aims of the Course are to provide a comprehensive and sound understanding of the theory and practice of tablet granulation and compression and to appreciate the various processes batch or continuous, that are available. The importance of the granulation process in producing good quality tablets will be emphasized. The modern techniques of extrusion, spheronisation, powder layering, roller compaction, fluid-bed processing, spray drying, melt extrusion, oral dispersion technology and tablet compression will be covered. The Course will be taught primarily by industrial scientists who have been closely involved with investigating these granulation and compression processes and thus a pragmatic approach will be adopted throughout.


  1. Methods and Reasons for Granulating
  2. Excipients
  3. Properties of Granules
  4. Granulation for Controlled Release
  5. High Speed Granulation and End-Point Control
  6. Integrated Mixer-Granulator Dryers
  7. Fluid Bed Granulation
  8. Layering
  9. Spray Drying
  10. Pellet Manufacture
  11. Extrusion and Spheronization
  12. Hot Melt Extrusion
  13. Roller Compaction
  14. Compression Theory
  15. Compression Machinery
  16. Compaction Simulators
  17. Tabletting and Tooling Problems
  18. Oral Dispersion Tabletting Technology
  19. Scale-Up, Transfer Technology and Supac


All who are working in pharmaceutical research, formulation, development, production, QA/QC and registration who require a sound understanding of the various granulation and compression methods and who wish to appreciate some of the advantages of the newer methods of granulation, spheronisation, roller compaction, layering, melt extrusion and compression that are now available.


The Papandayan Hotel / The Jayakarta Suites, Boutique Hotel and spa


Ir. Chandra Wahyu Purnomo


Biaya pelatihan sebesar Rp 7.500.000/peserta Non residensial. Khusus untuk pengiriman 3 peserta dari perusahaan yang sama, biaya pendaftaran sebesar Rp.7.000.000


  • Meeting room at Hotel *****
  • Module / Handout
  • Training Kit
  • 2x Coffee Break & Lunch
  • Flashdisk berisi materi
  • Exclusive Gifts
  • Certificate
  • Transportation during training

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